|
KMID : 0191120110260020243
|
|
Journal of Korean Medical Science
2011 Volume.26 No. 2 p.243 ~ p.249
|
|
|
The Correlation between Thyrotropin and Dyslipidemia in a Population-based Study
|
|
Lu Li
Wang Beibei
Shan Zhongyan
Jiang Fengwei
Chen Yanyan
Lai Yaxin
Wang Jiani
Xue Haibo
Wang Sen
Li Chenyan
Liu He
Li Ningna
Yu Jiashu
Shi Liangfeng
Hou Xin
Xing Qian
Teng Weiping
|
|
|
Abstract
|
|
|
|
This study investigated the relationship between serum thyrotrophin levels and dyslipidemia in subclinical hypothyroid and euthyroid subjects. A total of 110 subjects with subclinical hypothyroidism and 1,240 euthyroid subjects enrolled in this study. Patients with subclinical hypothyroidism had significantly lower high density lipoprotein cholesterol (HDL-C) levels than those who were euthyroid. The lipid profiles were each categorized and mean thyrotrophin levels were higher in subjects in the dyslipidemia subclasses than subjects in the normal subclasses. Thyrotrophin was positively associated with serum triglyceride and negatively associated with serum HDL-C in women. Thyrotrophin was also positively associated with total cholesterol (TC) in the overweight population along with TC and LDL-C in overweight women. In the euthyroid population, thyrotrophin was positively associated with TC in the overweight population. In conclusion, serum thyrotrophin was correlated with dyslipidemia in subclinical hypothyroid and euthyroid subjects; the correlation was independent of insulin sensitivity.
|
|
|
KEYWORD
|
|
|
Thyrotropin, Total Cholesterol, Cholesterol, LDL, Triglyceride, Cholesterol, HDL
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
    
|